March 2015 edition – Vol.7 no.3

4th edition of the ReSMiQ Innovation day (RID2015)
In order to ensure the greatest possible participation, the date of the next edition of the ReSMiQ Innovation Day is postponed to 15 October 2015. Also we remind you that this competition is open to all full-time students enrolled in a university or a college/CEGEP in the province of Québec. The project application deadline is May 4, 2015.. We are counting on all members to encourage their students to participate. More details

General Assembly of members
We remind all members of ReSMiQ that our next general assembly will be held on May 7, 2015 at Polytechnique Montréal. We will present the annual report of our activities and the attending members will vote on the Director’s election for the next term.

NEWS FROM OUR MEMBERS

Exposure
– Dr. Sawan from Polytechnique Montréal presented an invited seminar entitled “Engineering Neurosensing and Treatment Through Heterogenous Devices“ at the Hong Kong University of Science and Technology (HKUST).

– Dr. Martel from Polytechnique Montréal and his research are the subject of an article about nanoparticles and cancer treatment in La Presse.
Full article

Achievement
– Dr. Nabki and Dr. Ménard from Université du Québec à Montréal are launching a major project in the field of telecommunications with their partner Aeponyx and supported by NSERC through a RDC grant. More details

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RESMIQ’S ACTIVITIES

Seminars

ReSMiQ and the Chapter of the IEEE Solid-State Circuits Society (SSCS) in collaboration with the IEEE Circuits and Systems Society (CASS) invite you to attend the following seminar to be held on April 13, 2015, at 10:00 am at Polytechnique Montréal.
BajRossi
Speaker: Camilla Baj-Rossi , École polytechnique fédérale de Lausanne, Switzerland

Title: Implantable Device for Monitoring Drugs and Metabolites in Small Animals for Applications in Personalized Medicine
Abstract and biography

Intensive course

ReSMiQ Chapters of the IEEE Solid-State Circuits Society (SSCS) in collaboration with the IEEE Circuits and Systems Society (CASS) invites you to attend the following seminar to be held on May 14, 2015, at 10:30 AM at Polytechnique Montréal.
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Speaker: Carlos Galup-Montoro , Universidade Federal de Santa Catarina (UFSC), Brazil

Title: Ultra-Low-Voltage (ULV) IC Design
Abstrac and biography

ReSMiQ annual symposium
Date: Mai 29, 2015
Place:
Université du Québec à Rimouski (UQAR)
Important:
Transport and lodging for our members will be partially supported
by ReSMiQ.
You must register before April 12 to benefit from the reduced fees.

Financial support and Scholarships

– Financial support for undergraduate students
A financial support of 2000$ for 3 month starting May 1st for undergraduate students supervised by a member of ReSMiQ.
APPLICATION DEADLINE: April 7, 2015.
More details

– Microsystems Experimental Demonstration Competition
Undergraduate and graduate students are invited to demonstrate their scientific and technical expertise during the 4th edition of the ReSMiQ Innovation Day by submitting their project. More than 5 000$ in awards.
APPLICATION DEADLINE: Mai 4, 2015.
More details


SIGNAL is the main monthly information medium of the Microsystems Strategic Alliance of Québec (ReSMiQ). This newsletter aims to be an active link between the members of ReSMiQ and all individuals who have an interest in research and innovation in microsystems. We commit ourselves to promote in it our members’ research and increase ReSMiQ’s visibility.

ReSMiQ is a group of researchers in an interuniversity research center that can count on the support of the Fonds de recherche du Québec – Nature et technologies (FRQNT) and ten (10) Quebec universities involved in microsystems research.

Posted in Uncategorized

UPCOMING CONFERENCES

Call for contributions

12th NAMIS international Autumn school,
from september 10 to 14, 2018, Seattle, USA.

Submission deadline : May 18, 2018.
More details

Conference on Design and Architectures for Signal and Image Processing (DASIP),
du 9 au 12 octobre 2018, Porto, Portugal.
Submission deadline : May 25, 2018.
More details

IEEE Biomedical Circuits and Systems Conference (BioCAS2018),
from October 17 to 19, 2018, Cleveland, U.S.A.
Submission deadline : June 11, 2018.
More details

IEEE Life Science Conference (LSC2018),
from October 28 to 30, 2018, Montréal, Canada

Submission deadline : June 4, 2018.
More details

Call for participation

31st Canadian Conference on Electrical & Computer engineering (CCECE),
from May 13 to 16, 2018, Québec, Canada.
More details

2018 International Symposium on Circuits and Systems (ISCAS),
from May 27 to 30, 2018, Florence, Italy.

More details

16th IEEE International NEWCAS Conference (NEWCAS),
from June 24 to 27, 2018, Montréal, Canada.
More details

The 31st International Conference on Industrial, Engineering & Other Applications of Applied Intelligent Systems (IAE-AIE2018),
from June 25 to 28, 2018, Montréal, Canada.
More details

18th International Forum on MPSoC for Software-defined Hardware (MPSoC’18),
from July 29 to August 3, 2018, Snowbird, UT, USA.

More details

61st IEEE International Midwest Symposium on Circuits and Systems (MWSCAS),
from August 5 to 8, 2018, Windsor, ON, Canada.
More details

12th International Conference on Verification and Evaluation of Computer and Communication Systems (VECoS 2018),
du 26 au 28 septembre 2018, Grenoble, France.

Plus de détails

XXXIII  Conference on design of circuits and integrated systems (DCIS),
from November 14 to 16, 2018, Lyon, France.
More details

MEMBER PROFILE

Prof. Sylvain Martel
Polytechnique Montréal
Member of ReSMiQ since 2001

sylvain-martel_50Sylvain Martel received the Ph.D. degree in Electrical Engineering from McGill University, Montreal, Canada. Following his postdoctoral studies at the Massachusetts Institute of Technology (MIT), he was appointed Research Scientist at the BioInstrumentation Laboratory at MIT. Dr. Martel had several positions in the Canadian Naval Reserve as ship’s diver and supervisor, navigator, operations officer and participated in several NATO exercises. He had dual appointments at MIT and as Assistant Professor in the Department of Computer Engineering and the Institute of Biomedical Engineering at Polytechnique Montréal (PM). He is currently Professor in the Department of Computer Engineering and Director of the NanoRobotics Laboratory at PM that he founded in 2002. Dr. Martel holds the Canada Research Chair (CRC) in Micro and Nanosystem Development, Fabrication, and Validation. He has filed six patents, is the author or coauthor of more than 200 refereed publications, gives several invited presentations annually, and he is an active member of many international committees and organizations worldwide. Professor Martel has received several awards and distinctions such as the Queen Elizabeth II Diamond Jubilee Medal, the ACFAS - Jacques-Rousseau Award, the Innovator of the year by Montreal In Vivo, among other distinctions from international conferences, institutions and mass media. He recently received the title of IEEE Fellow for his contributions to medical micro- and nano-robotic and he is also Fellow of the Canadian Academy of Engineering. More information

Below is a selection of publications in recent years followed by representative work.

Lalande V., Gosselin F.P., Vonthron M., Conan B., Tremblay C., Beaudoin G., Soulez G., and Martel S., “In vivo demonstration of magnetic guidewire steerability in a MRI system with additional gradient coils”, Medical Physics, 42, 969-976, 2015.

Bigot, A.; Tremblay, C.; Soulez, G.; Martel, S., "Magnetic Resonance Navigation of a Bead Inside a Three-Bifurcation PMMA Phantom Using an Imaging Gradient Coil Insert", IEEE Transactions on Robotics, vol.30, no.3, pp. 719-727, 2014.

Martel S., Taherkhani S., Tabrizian M., Mohammadi M., de Lanauze D., and Felfoul O., "Computer 3D Controlled Bacterial Transports and Aggregations of Microbial Adhered Nano-components," Invited paper, Journal of Micro-Biorobotics, , Vol. 9, Issue 1-2, pp 23-28, 2014.

De Lanauze, D., Felfoul, O., Turcot, J.-P., Mohammadi, M., Martel, S. Three-Dimensional Remote Aggregation and Steering of Magnetotactic Bacteria Microrobots for Drug Delivery Applications. International Journal of Robotics Research, 33(3), p. 359-374, 2014.

Vidal, G., Martel, S. Measuring the Magnetophoretic Characteristics of Magnetic Agents for Targeted Diagnostic or Therapeutic Interventions in the Vascular Network. Journal of Micro-Bio Robotics, 8(2), p. 65-71, 2013.

Olamaei, N., Cheriet, F., Martel, S. Magnetic Resonance Imaging of Microvessels Using Iron-Oxide Nanoparticles. Journal of Applied Physics, 113(12), 2013.

Sharafi, A., Olamaei, N., Martel, S. A New Communication Method for Untethered Intelligent Microrobots. 2013 IEEE, p. 559-564, 2013.

RESEARCH CONTRIBUTIONS

Magnetic Resonance Navigation of a Bead Inside a Three-Bifurcation PMMA Phantom Using an Imaging Gradient Coil Insert

MRN is a fairly new technique which exploits both the high magnetic field of an MRI scanner and the magnetic gradients generated by a coil to steer a carrier vehicle embedding a functional drug inside the human vessel network. Such technology is a promising research area which aims at improving the localized delivery of theranostics agents toward a disease region of the body while maintaining low systemic drug concentration (see Fig. 1). MRN can potentially improve therapies such as liver and brain chemoembolization by serially navigating single boluses to a disease site to reach a given dose locally. This paper reports the successful navigation of a 1-mm Chrome-Steel bead along three consecutive polymethyl methacrylate channels inside the bore of a 1.5-T magnetic resonance imaging (MRI) scanner (see Fig. 2). The bead traveled at a mean velocity of 14 cm s-1. This was accomplished using an imaging gradient coil (IGC) insert located inside the MRI tube. While targeting one side of a bifurcation has been previously demonstrated using unidirectional gradient coils, this is the first time that magnetic resonance navigation (MRN) of a bead along consecutive channels is reported. Experimental results confirm that a clinical regular MRI can be used to propel a 1-mm device. In addition, when used at maximum power, IGC temperature rise becomes a serious issue that can ultimately damage the insert and limit the overall performance. Consequently, this paper aims to give some insight into coil temperature management for IGC-assisted procedures. A 33-min thermal stress test was carried out using 100% of the IGC power. Steady-state oscillation can be reached by interleaving propulsion periods with cooling periods, thus enabling longer propulsion procedures. Experimental data showed that the cooling time can be used for imaging purposes with no performance loss, thus enabling MRN-assisted procedures with multiplexed particle distribution assessment.
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 Fig. 1: Representation of a vascular network. Empty circles are microvectors embedding imaging or therapeutic agents. (a) Current chemoembolization procedure is done by injecting chemotherapeutic drug from a catheter—the injection site—toward a tumor with no control over the injected particles. (b) By correctly applying consecutive magnetic gradients G1, G2, and G3, MRN-assisted chemoembolization could potentially enable the control of the injected vectors to serially navigate them from the injection site toward the disease site (dashed line), thus preserving parenchyma healthy tissues.

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Fig. 2: Navigation of Bead Inside a Phantom. Each row represents a different time frame for the propulsion sequence − + −. The first column contains raw images of the footage. Arrows indicate the bead location and the black lines indicate the edges of the channel. The second column schematically depicts the evolution and the current state (blue coloring) of x-, y-, and z-gradients at the corresponding time frame. The directions of the gradients are shown in the top-left.